Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.48 |
| ▸ | DRD3 | P35462 | 4/20 | 0.48 |
| ▸ | DRD1 | P21728 | 4/20 | 0.47 |
| ▸ | DRD5 | P21918 | 4/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11457319 | 0.78 | DRD2 (0.54) | DRD2DRD3DRD1DRD5DRD4 | |
| SCHEMBL29052386 | 0.77 | MEN1 (0.57) | DRD2DRD3DRD1DRD5CA1 | |
| SCHEMBL11463967 | 0.77 | HTR2A (0.45) | DRD2CA2CA9ACHEADRA2A | |
| SCHEMBL11468318 | 0.75 | ADRA2A (0.43) | CA1CA2CA9CA14ADRA2A | |
| SCHEMBL1265672 | 0.74 | RYR2 (0.62) | DRD2DRD3DRD1DRD5DRD4 | |
| Hydrochloric Acid SCHEMBL11476372 | 0.72 | DRD2 (0.48) | DRD2DRD3DRD1DRD5DRD4 | |
| SCHEMBL11467866 | 0.72 | SMN1; SMN2 (0.52) | — | |
| Hydrochloric Acid SCHEMBL11457812 | 0.71 | HRH3 (0.46) | DRD2DRD3DRD1DRD5DRD4 | |
| SCHEMBL30468516 | 0.70 | ESR2 (0.47) | DRD2DRD3DRD1DRD5DRD4 | |
| SCHEMBL3698679 | 0.70 | DRD1 (0.86) | DRD2DRD3DRD1DRD5DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4233217-A | USED AS ANALGESICS, NARCOTIC ANTAGONISTS, AND ANTIHISTAMINES | PENNWALT CORPORATION (US) | 1980-11-11 | — | — | US | disclosed |
| US-4210749-A | USED AS ANALGESICS, NARCOTIC ANTAGONISTS | PENNWALT CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |