Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 3/20 | 0.40 |
| ▸ | DRD5 | P21918 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11459473 | 0.71 | KMT2A (0.48) | MTNR1BMTNR1AALDH1A1 | |
| SCHEMBL11455786 | 0.71 | KMT2A (0.50) | MTNR1BMTNR1ADRD1DRD5DRD2 | |
| SCHEMBL11467866 | 0.70 | SMN1; SMN2 (0.52) | ALDH1A1 | |
| SCHEMBL30468516 | 0.69 | ESR2 (0.47) | MTNR1BMTNR1ADRD1DRD5DRD2 | |
| SCHEMBL11456231 | 0.69 | DRD2 (0.48) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL6320426 | 0.67 | MTNR1B (1.00) | MTNR1BMTNR1A | |
| Hydrochloric Acid SCHEMBL11457319 | 0.67 | DRD2 (0.54) | DRD1DRD5DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL11455605 | 0.65 | HRH3 (0.51) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL26668032 | 0.64 | KMT2A (0.55) | MTNR1BDRD1NOTUMCA12CA1 | |
| SCHEMBL10351344 | 0.64 | ESR1 (0.62) | MTNR1BDRD1DRD5DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4233217-A | USED AS ANALGESICS, NARCOTIC ANTAGONISTS, AND ANTIHISTAMINES | PENNWALT CORPORATION (US) | 1980-11-11 | — | — | US | disclosed |
| US-4210749-A | USED AS ANALGESICS, NARCOTIC ANTAGONISTS | PENNWALT CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |