Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2255462 | 0.82 | ALDH1A1 (0.50) | MAPTTDP1ALDH1A1HPGDTSHR | |
| SCHEMBL30536022 | 0.78 | MAOA (0.42) | MAPTTDP1ALDH1A1HPGDTSHR | |
| SCHEMBL8942379 | 0.78 | LMNA (0.52) | MAPTTDP1ALDH1A1HPGDTSHR | |
| SCHEMBL10615370 | 0.78 | MAPT (0.38) | MAPTALDH1A1HPGDTSHRCYP3A4 | |
| SCHEMBL10582846 | 0.77 | TDP1 (0.39) | MAPTTDP1ALDH1A1HPGDTSHR | |
| SCHEMBL10437694 | 0.76 | MAPT (0.39) | MAPTTDP1ALDH1A1HPGDTSHR | |
| SCHEMBL10584520 | 0.75 | MAPT (0.36) | MAPTTDP1ALDH1A1HPGDTSHR | |
| SCHEMBL1581900 | 0.72 | GAA (0.39) | MAPTTDP1ALDH1A1HPGDLMNA | |
| SCHEMBL11204590 | 0.71 | MAPT (0.40) | MAPTTDP1ALDH1A1HPGDTSHR | |
| SCHEMBL27753606 | 0.71 | ALDH1A1 (0.42) | MAPTTDP1ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4203901-A | Process for making N-(N'-methylenepyrrolidonyl)-2-substituted anilines | GAF CORPORATION (US) | 1980-05-20 | — | — | US | disclosed |
| US-4202821-A | N-(N'-Methylenepyrrolidonyl)-2-substituted anilines | GAF CORPORATION (US) | 1980-05-13 | — | — | US | disclosed |
| US-4178168-A | Herbicidal n-(haloacetyl)-n-(n-methylene pyrrolidonyl)-2-oxyalkyleneoxyalkylanilines | GAF CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |