Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27577916 | 0.84 | LMNA (0.44) | LMNAMAPTALDH1A1HPGDGAA | |
| SCHEMBL2255462 | 0.83 | ALDH1A1 (0.50) | LMNAMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL30536022 | 0.80 | MAOA (0.42) | LMNAMAPTALDH1A1HPGDTDP1 | |
| SCHEMBL10582846 | 0.78 | TDP1 (0.39) | LMNAMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11455940 | 0.78 | MAPT (0.40) | LMNAMAPTALDH1A1HPGDGAA | |
| SCHEMBL10816354 | 0.78 | CYP1A2 (0.43) | LMNAMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL10437694 | 0.77 | MAPT (0.39) | LMNAMAPTALDH1A1HPGDGAA | |
| SCHEMBL1581900 | 0.77 | GAA (0.39) | LMNAMAPTALDH1A1HPGDGAA | |
| SCHEMBL10812357 | 0.77 | TSHR (0.47) | LMNAMAPTALDH1A1HPGDGAA | |
| SCHEMBL942342 | 0.75 | TSHR (0.41) | LMNAMAPTALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115650933-B | 3, 4-dihydro-3-methyl-2H-1, 4-benzoxazine and preparation method thereof | 威尔（福建）生物有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-115650933-B | 3, 4-dihydro-3-methyl-2H-1, 4-benzoxazine and preparation method thereof | 威尔（福建）生物有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-117064886-A | Method for reversing normal aging process and prolonging life | 麦姆德制药公司 | 2023-11-17 | — | — | CN | disclosed |
| US-5578711-A | Process for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-26 | — | — | US | disclosed |
| US-5541299-A | Process for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-07-30 | — | — | US | disclosed |
| US-5502171-A | Process for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | disclosed |
| US-4376728-A | Process for the preparation of cationic alkylarylhydrazone dyestuffs and color bases thereof | BAYER AKTIENGESELLSCHAFT (DE) | 1983-03-15 | — | — | US | disclosed |