Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11455506 | 0.84 | GRIA4 (0.38) | FFAR1MMP1MMP2MMP3MMP7 | |
| SCHEMBL11445061 | 0.77 | GRIA4 (0.47) | FFAR1MAPTPTGS2PPARGPPARA | |
| SCHEMBL11446013 | 0.75 | PTGS2 (0.45) | MAPTPTGS2ALDH1A1CTSSCTSK | |
| SCHEMBL11829130 | 0.74 | ALDH1A1 (0.50) | ACHEMAPTALDH1A1 | |
| SCHEMBL11446798 | 0.71 | FFAR1 (0.48) | FFAR1ACHEMAPTPTGS2GRIA4 | |
| SCHEMBL11445724 | 0.71 | LMNA (0.59) | FFAR1MAPTPTGS2AKR1C3AKR1C2 | |
| SCHEMBL11455719 | 0.71 | ALOX5 (0.45) | FFAR1MMP1MMP2MMP3MMP7 | |
| SCHEMBL11465011 | 0.71 | ALDH1A1 (0.43) | FFAR1MMP1MMP2MMP3MMP7 | |
| SCHEMBL2996427 | 0.69 | FFAR1 (0.61) | FFAR1ACHEMAPT | |
| SCHEMBL11445301 | 0.69 | HAO1 (0.42) | MMP1MMP2MMP3MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4191776-A | ANTITHROMBOTICS, ANTICHOLESTEREMICS, ANTICOAGULANTS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-03-04 | — | — | US | disclosed |
| US-4187225-A | Novel synthesis of bis pyrazolone oxonol dyes | POLAROID CORPORATION (US) | 1980-02-05 | — | — | US | disclosed |
| US-3993683-A | ANTITHROMBOTIC, ANTICHOLESTEREMICS, ANTICOAGULANTS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-11-23 | — | — | US | disclosed |