Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11456231 | 0.75 | DRD2 (0.48) | ADRA2AADRA2BADRA2CCA1CA2 | |
| SCHEMBL11463967 | 0.74 | HTR2A (0.45) | ADRA2AADRA2BADRA2CTSHRCRHBP | |
| SCHEMBL31619584 | 0.73 | CHRNB2 (0.49) | GRIN2BGRIN1ESR1 | |
| SCHEMBL18034964 | 0.72 | SLC6A4 (0.63) | GRIN2BGRIN1 | |
| SCHEMBL26956142 | 0.69 | OPRM1 (0.49) | TSHRCRHBPCRHR2ESR1 | |
| SCHEMBL13534235 | 0.68 | CHRNB2 (0.47) | CA2 | |
| SCHEMBL16624030 | 0.68 | SLC6A4 (0.48) | GRIN2BGRIN1 | |
| SCHEMBL1095522 | 0.67 | ESR1 (0.46) | ESR1 | |
| SCHEMBL607389 | 0.67 | CYP19A1 (0.52) | GRIN2BGRIN1ESR1 | |
| SCHEMBL10673432 | 0.66 | DRD1 (0.43) | TSHRCRHBPCRHR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4210749-A | USED AS ANALGESICS, NARCOTIC ANTAGONISTS | PENNWALT CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |