Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11466886 | 0.97 | SLC6A9 (0.46) | SLC6A9PPARGPPARA | |
| SCHEMBL11456914 | 0.89 | LTA4H (0.54) | SLC6A9LTA4HDRD2ALDH1A1LMNA | |
| SCHEMBL11448946 | 0.86 | LTA4H (0.51) | LTA4H | |
| SCHEMBL11458069 | 0.85 | SLC6A4 (0.53) | SLC6A9LTA4HDRD2ALDH1A1LMNA | |
| SCHEMBL11466698 | 0.85 | SLC6A4 (0.50) | LTA4HSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11449145 | 0.84 | LTA4H (0.40) | LTA4HSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11457674 | 0.83 | CHRNB4 (0.55) | LTA4H | |
| SCHEMBL11466699 | 0.83 | LTA4H (0.44) | LTA4HSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11449383 | 0.83 | GHSR (0.48) | LTA4HSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11466863 | 0.83 | GHSR (0.53) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4225608-A | ANTIDEPRESSANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-09-30 | — | — | US | disclosed |
| EP-0004288-A2 | Phenoxyalkyl amines, pharmaceutical compositions containing them, and process for their preparation | MERCK PATENT GmbH (DE) | 1979-10-03 | — | — | EP | disclosed |