Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.40 |
| ▸ | GHSR | Q92847 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11450652 | 0.89 | LTA4H (0.41) | LTA4HGHSRPOLBSLC6A2SLC6A4 | |
| SCHEMBL11456280 | 0.86 | GHSR (0.52) | LTA4HGHSRPOLBSLC6A2SLC6A4 | |
| SCHEMBL11449386 | 0.86 | GHSR (0.39) | LTA4HGHSRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11458221 | 0.84 | SLC6A9 (0.45) | LTA4HSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11448946 | 0.83 | LTA4H (0.51) | LTA4HGHSRPOLB | |
| SCHEMBL11466698 | 0.82 | SLC6A4 (0.50) | LTA4HPOLBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11455711 | 0.81 | POLB (0.39) | LTA4HPOLBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11466886 | 0.81 | SLC6A9 (0.46) | GHSR | |
| SCHEMBL11457674 | 0.80 | CHRNB4 (0.55) | LTA4HGHSRPOLBCYP2D6 | |
| SCHEMBL11449383 | 0.80 | GHSR (0.48) | LTA4HGHSRPOLBSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4225608-A | ANTIDEPRESSANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-09-30 | — | — | US | disclosed |
| EP-0004288-A2 | Phenoxyalkyl amines, pharmaceutical compositions containing them, and process for their preparation | MERCK PATENT GmbH (DE) | 1979-10-03 | — | — | EP | disclosed |