SCHEMBL1145830

SCHEMBL1145830

CSCc1ccccc1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.48
SMN1; SMN2 Q16637 3/20 0.46
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
CYP1A2 P05177 2/20 0.43
CYP3A4 P08684 2/20 0.43
CYP2D6 P10635 2/20 0.43
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
MAPT P10636 2/20 0.43
TSHR P16473 1/20 0.43
ACHE P22303 1/20 0.43
ALDH1A1 P00352 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
HPGD P15428 2/20 0.42
GAA P10253 1/20 0.42
THRB P10828 1/20 0.42
CHRM2 P08172 1/20 0.41
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29640378 0.86 GAA (0.45) KMT2AMEN1MAPTTSHRALDH1A1
SCHEMBL3083039 0.84 MAPT (0.39) TAAR1SMN1; SMN2KMT2ACYP1A2CYP3A4
SCHEMBL22342192 0.82 FFAR1 (0.40) TAAR1SMN1; SMN2MAPTTSHRACHE
SCHEMBL775626 0.82 TAAR1 (0.50) TAAR1SMN1; SMN2KMT2AMEN1CYP1A2
SCHEMBL777337 0.82 ALDH1A1 (0.56) TAAR1SMN1; SMN2KMT2AMEN1CYP1A2
SCHEMBL8757216 0.78 TAAR1 (0.46) TAAR1SMN1; SMN2KMT2AMEN1CYP1A2
SCHEMBL21654563 0.78 TAAR1 (0.46) TAAR1SMN1; SMN2KMT2AMEN1CYP1A2
SCHEMBL1145828 0.78 TAAR1 (0.46) TAAR1SMN1; SMN2KMT2AMEN1CYP1A2
SCHEMBL9976776 0.78 TAAR1 (0.46) TAAR1SMN1; SMN2KMT2AMEN1CYP1A2
SCHEMBL30139921 0.78 TAAR1 (0.52) TAAR1SMN1; SMN2KMT2AMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119717396-A Photosensitive resin composition baked at low temperature and use thereof 台湾永光化学工业股份有限公司 2025-03-28 CN claimed
EP-4081597-A1 UV RESISTANT SURFACING MATERIALS FOR COMPOSITE PARTS Cytec Industries, Inc. (US) 2022-11-02 EP claimed
WO-2021133972-A1 UV RESISTANT SURFACING MATERIALS FOR COMPOSITE PARTS CYTEC INDUSTRIES INC. (US) 2021-07-01 WO claimed
US-20070015755-A1 NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS AXYS PHARMACEUTICALS, INC. (US) 2007-01-18 US claimed
EP-1452522-A2 Novel compounds and compositions as protease inhibitors AXYS PHARMACEUTICALS, INC. (US) 2004-09-01 EP claimed
US-20040147745-A1 Novel compounds and compositions as protease inhibitors AXYS PHARMACEUTICALS, INC. (US) 2004-07-29 US claimed
EP-1178958-B1 N-CYANOMETHYL AMIDES AS PROTEASE INHIBITORS AXYS PHARM INC (US) 2004-02-18 EP claimed
US-20030096796-A1 Novel compounds and compositions as protease inhibitors AXYS PHARMACEUTICALS, INC. (US) 2003-05-22 US claimed
JP-2002539191-A 2002-11-19 JP claimed
US-6455502-B1 Compounds and compositions as protease inhibitors AXYS PHARMACEUTICALS, INC. 2002-09-24 US claimed
EP-1178958-A2 N-CYANOMETHYL AMIDES AS PROTEASE INHIBITORS AXYS PHARMACEUTICALS, INC. (US) 2002-02-13 EP claimed
WO-2000055125-A2 N-CYANOMETHYL AMIDES AS PROTEASE INHIBITORS AXYS PHARMACEUTICALS, INC. (US) 2000-09-21 WO claimed
US-12435237-B2 UV resistant surfacing materials for composite parts CYTEC INDUSTRIES INC. (US) 2025-10-07 US disclosed
WO-2025094854-A1 METHOD FOR PRODUCING POLYACID SALTS OR MIXTURES THEREOF, AND METHOD FOR REMOVING IMPURITIES 東京応化工業株式会社 2025-05-08 WO disclosed
CN-119717396-A Photosensitive resin composition baked at low temperature and use thereof 台湾永光化学工业股份有限公司 2025-03-28 CN disclosed
CN-118076706-A Color-changeable adhesive sheet and coloring method thereof 日东电工株式会社 2024-05-24 CN disclosed
EP-1178958-A2 N-CYANOMETHYL AMIDES AS PROTEASE INHIBITORS AXYS PHARMACEUTICALS, INC. (US) 2002-02-13 EP disclosed
EP-1112251-A1 AZETIDINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM Aventis Pharma S.A. (FR) 2001-07-04 EP disclosed
WO-2000055125-A2 N-CYANOMETHYL AMIDES AS PROTEASE INHIBITORS AXYS PHARMACEUTICALS, INC. (US) 2000-09-21 WO disclosed
WO-2000015609-A1 AZETIDINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM AVENTIS PHARMA S.A. (FR) 2000-03-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030096796-A1 Novel compounds and compositions as protease inhibitors CTRL, SERPINB1, CPN1 TAAR1 4777/4885SMN1; SMN2 3462/4885KMT2A 2983/4885
US-20040147745-A1 Novel compounds and compositions as protease inhibitors CTRL, SERPINB1, CPN1 TAAR1 4777/4885SMN1; SMN2 3462/4885KMT2A 2983/4885
US-20070015755-A1 NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS CTRL, SERPINB1, CPN1 TAAR1 4777/4885SMN1; SMN2 3462/4885KMT2A 2983/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.