Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1145830 | 0.82 | TAAR1 (0.48) | SMN1; SMN2L3MBTL1TSHRHPGDMAPT | |
| SCHEMBL22342193 | 0.81 | CSNK2A2 (0.42) | SMN1; SMN2NPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL15912540 | 0.78 | MAPK1 (0.42) | SMN1; SMN2NPC1RAB9AL3MBTL1TSHR | |
| SCHEMBL2208060 | 0.77 | DPP4 (0.54) | L3MBTL1HPGDHTR7ALOX5APFEN1 | |
| SCHEMBL3083039 | 0.77 | MAPT (0.39) | SMN1; SMN2MAPTTAAR1ALOX5APFEN1 | |
| SCHEMBL5599467 | 0.76 | CSNK2A2 (0.49) | FFAR1FFAR4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3858794 | 0.74 | PDCD1 (0.53) | FFAR1FFAR4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL13715511 | 0.74 | KCNN4 (0.41) | FFAR1FFAR4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11201350 | 0.74 | TAAR1 (0.45) | FFAR1FFAR4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5281352 | 0.74 | TAAR1 (0.40) | FFAR1FFAR4SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200255478-A1 | NOVEL COMPOUNDS ACTIVATING THE NRF2 PATHWAY | ALMIRALL SA (ES) | 2020-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255478-A1 | NOVEL COMPOUNDS ACTIVATING THE NRF2 PATHWAY | KEAP1, NFE2L2, HMOX1 | FFAR1 585/4885FFAR4 1982/4885SMN1; SMN2 2725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.