SCHEMBL29640378

SCHEMBL29640378

CS(=O)(=O)O.CSCc1ccccc1C

nearest known ligand 0.55

Known targets — ChEMBL curated mechanism

ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.45
ALDH1A1 P00352 7/20 0.44
HPGD P15428 5/20 0.44
LMNA P02545 5/20 0.43
HTT P42858 2/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
MAPT P10636 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
TSHR P16473 1/20 0.42
KDM4E B2RXH2 1/20 0.41
CHRM2 P08172 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1145830 0.86 TAAR1 (0.48) GAAALDH1A1HPGDLMNAHTT
SCHEMBL27864290 0.79 TAAR1 (0.42) GAAALDH1A1HPGDLMNAHTT
SCHEMBL8763554 0.77 CHRM2 (0.61) GAAALDH1A1HPGDLMNAHTT
SCHEMBL27764016 0.77 KMT2A (0.45) GAAALDH1A1HPGDLMNAHTT
SCHEMBL29634752 0.76 MAPT (0.51) ALDH1A1HPGDLMNAHTTMEN1
SCHEMBL6075489 0.76 TAAR1 (0.48) GAAALDH1A1HPGDHTTMEN1
SCHEMBL294361 0.72 LMNA (0.50) GAAALDH1A1HPGDLMNAHTT
SCHEMBL3083039 0.72 MAPT (0.39) LMNAHTTKMT2AMAPTCHRM2
SCHEMBL8080270 0.71 GAA (0.40) GAAMEN1KMT2A
SCHEMBL22342192 0.71 FFAR1 (0.40) ALDH1A1HPGDLMNAMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115103871-A Resin composition, cured film, laminate, method for producing cured film, and semiconductor device 富士胶片株式会社 2022-09-23 CN disclosed
CN-114981360-A Curable resin composition, cured film, laminate, method for producing cured film, and semiconductor device 富士胶片株式会社 2022-08-30 CN disclosed
CN-114730145-A Pattern forming method, photocurable resin composition, method for producing laminate, and method for producing electronic device 富士胶片株式会社 2022-07-08 CN disclosed
CN-114514470-A Pattern forming method, photosensitive resin composition, method for manufacturing laminate, and method for manufacturing semiconductor device 富士胶片株式会社 2022-05-17 CN disclosed