Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11454219 | 0.82 | NOTUM (0.63) | ALDH1A1POLBSMN1; SMN2TDP1HPGD | |
| SCHEMBL4898108 | 0.80 | NOTUM (0.62) | ALDH1A1NOTUM | |
| SCHEMBL11456565 | 0.79 | NOTUM (0.65) | ALDH1A1POLBSMN1; SMN2NOTUMMAPT | |
| SCHEMBL3491610 | 0.77 | NOTUM (0.64) | ALDH1A1CYP2C19POLBSMN1; SMN2TDP1 | |
| SCHEMBL11457533 | 0.72 | NOTUM (0.69) | ALDH1A1POLBTDP1NOTUML3MBTL1 | |
| SCHEMBL11463934 | 0.71 | MYC (0.56) | ALDH1A1POLBTDP1NOTUMKMT2A | |
| SCHEMBL6052352 | 0.71 | MAPT (0.65) | ALDH1A1POLBTDP1KMT2AMAPT | |
| SCHEMBL27981807 | 0.69 | TDP1 (0.52) | ALDH1A1SMN1; SMN2TDP1KMT2AMAPT | |
| SCHEMBL28604247 | 0.69 | HSD17B10 (0.56) | ALDH1A1CYP2C19POLBSMN1; SMN2TDP1 | |
| SCHEMBL15919337 | 0.69 | ALDH1A1 (0.61) | ALDH1A1CYP2C19POLBSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4238220-A | PLANT GROWTH REGULATORS; SEEDICIDES | ROHM AND HAAS COMPANY (US) | 1980-12-09 | — | — | US | disclosed |