Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.58 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11284205 | 1.00 | KDM4E (0.58) | KDM4ECYP1A2PTGDR2ALDH1A1CYP2C19 | |
| SCHEMBL11460695 | 1.00 | KDM4E (0.58) | KDM4ECYP1A2PTGDR2ALDH1A1CYP2C19 | |
| SCHEMBL15689214 | 0.92 | KDM4E (0.52) | KDM4ECYP1A2PTGDR2ALDH1A1CYP2C19 | |
| SCHEMBL9768642 | 0.89 | ALDH1A1 (0.62) | KDM4ECYP1A2PTGDR2ALDH1A1CYP2C19 | |
| SCHEMBL15689086 | 0.86 | PTGS2 (0.67) | KDM4ECYP1A2PTGDR2ALDH1A1CYP2C19 | |
| SCHEMBL11463625 | 0.85 | MAPK14 (0.53) | KDM4ECYP1A2PTGDR2ALDH1A1CYP2C19 | |
| SCHEMBL11752931 | 0.84 | KDM4E (0.55) | KDM4ECYP1A2PTGDR2ALDH1A1CYP2C19 | |
| SCHEMBL21670773 | 0.84 | PTGS2 (0.56) | KDM4ECYP1A2PTGDR2ALDH1A1CYP2C19 | |
| SCHEMBL11755296 | 0.84 | KDM4E (0.55) | KDM4ECYP1A2PTGDR2ALDH1A1CYP2C19 | |
| SCHEMBL27690448 | 0.84 | PTGS2 (0.55) | KDM4ECYP1A2PTGDR2ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4197306-A | CONTROL OF INSECTS AND ACARIDS | UNIROYAL, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153703-A | Method of controlling insects and acarids with certain aryl-substituted thiazoles | UNIROYAL, INC. (US) | 1979-05-08 | — | — | US | disclosed |