SCHEMBL9768642

SCHEMBL9768642

c1ccc(-c2nc(-c3ccccc3)c(-c3ccccc3)s2)cc1

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.62
CYP1A2 P05177 2/20 0.62
CYP2D6 P10635 2/20 0.62
CYP2C19 P33261 2/20 0.62
MAPT P10636 2/20 0.62
PTGS2 P35354 2/20 0.59
KDM4E B2RXH2 3/20 0.55
CYP3A4 P08684 1/20 0.55
GAA P10253 1/20 0.55
CYP2C9 P11712 1/20 0.55
CDC7 O00311 4/20 0.53
DBF4 Q9UBU7 4/20 0.53
ALOX5 P09917 4/20 0.51
PTGDR2 Q9Y5Y4 2/20 0.51
POLB P06746 1/20 0.51
CCNE1 P24864 1/20 0.50
CDK2 P24941 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21670773 0.91 PTGS2 (0.56) ALDH1A1CYP1A2CYP2D6CYP2C19MAPT
SCHEMBL11456658 0.91 CDC7 (0.67) ALDH1A1CYP1A2CYP2D6CYP2C19MAPT
SCHEMBL16011062 0.89 ALOX5 (0.50) ALDH1A1CYP1A2CYP2D6CYP2C19MAPT
SCHEMBL11284205 0.89 KDM4E (0.58) ALDH1A1CYP1A2CYP2D6CYP2C19MAPT
SCHEMBL12245630 0.89 ALOX5 (0.69) ALDH1A1CYP1A2CYP2D6CYP2C19MAPT
SCHEMBL9958269 0.89 ALDH1A1 (0.51) ALDH1A1CYP1A2CYP2D6CYP2C19MAPT
SCHEMBL11462189 0.89 KDM4E (0.58) ALDH1A1CYP1A2CYP2D6CYP2C19MAPT
SCHEMBL11287147 0.89 PTGS2 (0.74) ALDH1A1CYP1A2CYP2D6CYP2C19MAPT
SCHEMBL11460695 0.89 KDM4E (0.58) ALDH1A1CYP1A2CYP2D6CYP2C19MAPT
SCHEMBL11452752 0.86 ALOX5 (0.73) ALDH1A1MAPTPTGS2KDM4EALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114981451-A Nucleotide probe 索尼集团公司 2022-08-30 CN claimed
CN-112399996-A Polymeric dyes having a backbone comprising organophosphate units 索尼公司 2021-02-23 CN claimed
US-5053302-A Photosensitivity, durability FUJI PHOTO FILM CO., LTD. (JP) 1991-10-01 US claimed
US-4197306-A CONTROL OF INSECTS AND ACARIDS UNIROYAL, INC. (US) 1980-04-08 US claimed
CN-117661051-A Composition, application thereof, leveling agent and preparation method thereof 华为技术有限公司 2024-03-08 CN disclosed
CN-110627739-B Method for synthesizing thiazole heterocyclic compound through photocatalysis 桂林医学院 2023-02-07 CN disclosed
CN-114981451-A Nucleotide probe 索尼集团公司 2022-08-30 CN disclosed
CN-114806218-A Super bright dimeric or polymeric dyes 索尼公司 2022-07-29 CN disclosed
CN-109415574-B Superbright dimeric or polymeric dyes with rigid spacer groups 索尼公司 2021-05-28 CN disclosed
CN-112399996-A Polymeric dyes having a backbone comprising organophosphate units 索尼公司 2021-02-23 CN disclosed
CN-110627739-A Method for synthesizing thiazole heterocyclic compound through photocatalysis 桂林医学院 2019-12-31 CN disclosed
US-9287515-B2 Compositions comprising organic and organometallic compounds, and their applications in organic electroluminescence, light emission, display, and illumination devices UDC Ireland (IE) 2016-03-15 US disclosed
US-20120153272-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed
US-5053302-A Photosensitivity, durability FUJI PHOTO FILM CO., LTD. (JP) 1991-10-01 US disclosed
US-4612271-A Photosensitive composition comprising azo compounds FUJI PHOTO FILM CO., LTD. (JP) 1986-09-16 US disclosed
US-4322428-A 2(4-Fluorophenyl)-4,5,-bis(4-methoxyphenyl)thiazole and method of use ELI LILLY AND COMPANY (US) 1982-03-30 US disclosed
EP-0037274-A1 Substituted triaryl thiazole compounds ELI LILLY AND COMPANY (US) 1981-10-07 EP disclosed
US-4197306-A CONTROL OF INSECTS AND ACARIDS UNIROYAL, INC. (US) 1980-04-08 US disclosed
US-4153703-A Method of controlling insects and acarids with certain aryl-substituted thiazoles UNIROYAL, INC. (US) 1979-05-08 US disclosed