Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11191391 | 0.85 | KMT2A (0.53) | LMNAPKMMAPK1TP53KMT2A | |
| SCHEMBL11459823 | 0.82 | KMT2A (0.49) | LMNAPKMMAPK1TP53KMT2A | |
| SCHEMBL9482767 | 0.79 | HSD17B10 (0.44) | LMNAPKMMAPK1TP53KMT2A | |
| SCHEMBL11467996 | 0.78 | KMT2A (0.44) | LMNAPKMMAPK1TP53KMT2A | |
| SCHEMBL11188195 | 0.76 | HSD17B10 (0.41) | LMNAPKMMAPK1TP53KMT2A | |
| SCHEMBL9487176 | 0.76 | HSD17B10 (0.40) | LMNAPKMMAPK1TP53KMT2A | |
| SCHEMBL11466635 | 0.75 | HSD17B10 (0.39) | LMNAPKMMAPK1TP53KMT2A | |
| SCHEMBL11183535 | 0.72 | CA2 (0.41) | LMNAPKMMAPK1TP53HPGD | |
| SCHEMBL9494990 | 0.71 | PTGS1 (0.35) | LMNAKMT2AMEN1HPGDHSD17B10 | |
| SCHEMBL25328341 | 0.71 | LMNA (0.62) | LMNAPKMMAPK1TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4208202-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1980-06-17 | — | — | US | claimed |