Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11191391 | 0.93 | KMT2A (0.53) | KMT2ALMNAMEN1HPGDPKM | |
| SCHEMBL11459823 | 0.91 | KMT2A (0.49) | KMT2ALMNAMEN1HPGDPKM | |
| SCHEMBL9494990 | 0.81 | PTGS1 (0.35) | KMT2ALMNAMEN1HPGDPTGS1 | |
| SCHEMBL11380592 | 0.80 | LMNA (0.47) | KMT2ALMNAMEN1HPGDPTGS1 | |
| SCHEMBL11376209 | 0.79 | LMNA (0.46) | KMT2ALMNAMEN1HPGDPTGS1 | |
| SCHEMBL11378345 | 0.79 | LMNA (0.46) | KMT2ALMNAMEN1HPGDPTGS1 | |
| SCHEMBL11462273 | 0.78 | LMNA (0.52) | KMT2ALMNAMEN1HPGDPKM | |
| SCHEMBL11182644 | 0.77 | PTGS1 (0.41) | KMT2AMEN1PTGS1PTGS2 | |
| SCHEMBL11488482 | 0.75 | PTGS2 (0.40) | PTGS1PTGS2BRD4 | |
| SCHEMBL9482767 | 0.73 | HSD17B10 (0.44) | KMT2ALMNAMEN1HPGDPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4208202-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1980-06-17 | — | — | US | disclosed |