Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ADK | P55263 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9277531 | 0.74 | TP53 (0.48) | SMN1; SMN2L3MBTL1TP53ALDH1A1TSHR | |
| SCHEMBL7532078 | 0.72 | SMN1; SMN2 (0.37) | SMN1; SMN2L3MBTL1SLC29A1ADKALDH1A1 | |
| SCHEMBL9720130 | 0.72 | ALDH1A1 (0.34) | L3MBTL1ALDH1A1 | |
| SCHEMBL1950950 | 0.69 | L3MBTL1 (0.52) | SMN1; SMN2L3MBTL1TP53ALDH1A1NPC1 | |
| SCHEMBL8216015 | 0.69 | L3MBTL1 (0.39) | SMN1; SMN2L3MBTL1TP53PKMALDH1A1 | |
| SCHEMBL8835861 | 0.64 | SMN1; SMN2 (0.44) | SMN1; SMN2L3MBTL1SLC29A1ADKALDH1A1 | |
| SCHEMBL15882840 | 0.64 | EGFR (0.47) | L3MBTL1TP53ALDH1A1 | |
| SCHEMBL10965684 | 0.64 | SMN1; SMN2 (0.40) | SMN1; SMN2L3MBTL1TP53SLC29A1ADK | |
| SCHEMBL11193955 | 0.63 | PKM (0.42) | SMN1; SMN2L3MBTL1TP53PKMALDH1A1 | |
| SCHEMBL2563782 | 0.62 | KMT2A (0.50) | TP53PKMALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55076866-A | — | — | None | — | — | JP | disclosed |
| JP-S5576866-A | PREPARATION OF 5-FLUOROURACIL DERIVATIVE | SANKYO CO LTD | 1980-06-10 | — | — | JP | disclosed |