Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | STK17B | O94768 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11462866 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1RAB9ASLC29A1ALDH1A1 | |
| SCHEMBL12436875 | 0.68 | GABRA5 (0.42) | CYP1A2CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL907669 | 0.68 | KDM4E (0.37) | CYP1A2CYP3A4KDM4EMAPTALDH1A1 | |
| SCHEMBL27462404 | 0.68 | SMN1; SMN2 (0.32) | SMN1; SMN2SLC22A12 | |
| SCHEMBL27845043 | 0.65 | AGBL2 (0.41) | SMN1; SMN2CYP1A2CYP3A4KDM4EMAPT | |
| SCHEMBL907750 | 0.65 | HSD17B10 (0.39) | CYP1A2CYP3A4KDM4EMAPTALDH1A1 | |
| SCHEMBL8216015 | 0.63 | L3MBTL1 (0.39) | SMN1; SMN2L3MBTL1CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL1950950 | 0.63 | L3MBTL1 (0.52) | SMN1; SMN2L3MBTL1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8835861 | 0.62 | SMN1; SMN2 (0.44) | SMN1; SMN2L3MBTL1RAB9AKDM4EMAPT | |
| SCHEMBL15882840 | 0.61 | EGFR (0.47) | L3MBTL1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0731095-B1 | 4-Alkylthio-pyrimidin-5-ylacetic acid derivatives | BAYER AG (DE) | 2002-07-03 | — | — | EP | disclosed |
| EP-0731095-B1 | 4-Alkylthio-pyrimidin-5-ylacetic acid derivatives | BAYER AG (DE) | 2002-07-03 | — | — | EP | disclosed |
| US-5776941-A | FUNGICIDES | SANDOZ LTD (CH) | 1998-07-07 | — | — | US | disclosed |
| US-5776941-A | FUNGICIDES | SANDOZ LTD (CH) | 1998-07-07 | — | — | US | disclosed |
| US-5776941-A | FUNGICIDES | SANDOZ LTD (CH) | 1998-07-07 | — | — | US | disclosed |
| CN-1139671-A | 4-alkylsulfur pyrimidine-5-acetous derivant | SANDOZ LTD (CH) | 1997-01-08 | — | — | CN | disclosed |
| EP-0731095-A1 | 4-Alkylthio-pyrimidin-5-ylacetic acid derivatives | SANDOZ LTD. (CH) | 1996-09-11 | — | — | EP | disclosed |
| EP-0731095-A1 | 4-Alkylthio-pyrimidin-5-ylacetic acid derivatives | SANDOZ LTD. (CH) | 1996-09-11 | — | — | EP | disclosed |
| EP-0731095-A1 | 4-Alkylthio-pyrimidin-5-ylacetic acid derivatives | SANDOZ LTD. (CH) | 1996-09-11 | — | — | EP | disclosed |