SCHEMBL20152373

SCHEMBL20152373

CCSc1cc(C)ccc1C(=O)Cl

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
ALOX15 P16050 2/20 0.36
HPGD P15428 2/20 0.36
GAA P10253 2/20 0.36
TP53 P04637 2/20 0.36
LMNA P02545 1/20 0.36
ALOX12 P18054 1/20 0.36
HSD17B10 Q99714 1/20 0.36
RAB9A P51151 7/20 0.36
NPC1 O15118 6/20 0.36
SMN1; SMN2 Q16637 4/20 0.36
MAPK1 P28482 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
ALDH1A1 P00352 4/20 0.35
JAK2 O60674 1/20 0.35
KDM4E B2RXH2 1/20 0.35
CASP3 P42574 1/20 0.35
SENP7 Q9BQF6 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24490704 0.84 GAA (0.40) MAPTMEN1KMT2AALOX15HPGD
SCHEMBL20152377 0.84 CSNK2A1 (0.47) MEN1KMT2ARAB9ANPC1SMN1; SMN2
SCHEMBL6225818 0.82 MEN1 (0.41) MAPTMEN1KMT2AALOX15HPGD
SCHEMBL10333744 0.82 MAPT (0.43) MAPTMEN1KMT2AALOX15HPGD
SCHEMBL20482053 0.81 PTPRC (0.46) MAPTALOX15HPGDGAALMNA
SCHEMBL11463582 0.80 MEN1 (0.39) MAPTMEN1KMT2AALOX15HPGD
SCHEMBL18544164 0.78 CES2 (0.42) HPGDGAAHSD17B10SMN1; SMN2L3MBTL1
SCHEMBL2747139 0.77 HSD17B10 (0.49) MAPTKMT2AALOX15HPGDLMNA
SCHEMBL18050194 0.75 HPGD (0.40) MAPTMEN1KMT2AALOX15HPGD
SCHEMBL14808369 0.74 HSD17B1 (0.40) MEN1KMT2AHPGDLMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180132482-A1 ANTHRANILIC ACID ESTER COMPOUND OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL MICROBICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE MICROBICIDE NIHON NOHYAKU CO., LTD. (JP) 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180132482-A1 ANTHRANILIC ACID ESTER COMPOUND OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL MICROBICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE MICROBICIDE HACL2, SLC11A2, HDHD5 MAPT 4800/4885MEN1 1425/4885KMT2A 783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.