SCHEMBL302204

SCHEMBL302204

Cc1ccc(C(=O)Cl)c(C(=O)Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 1/20 0.48
HDAC7 Q8WUI4 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
NFE2L2 Q16236 1/20 0.41
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39
RAB9A P51151 5/20 0.39
NPC1 O15118 4/20 0.39
KDM4E B2RXH2 2/20 0.39
HPGD P15428 1/20 0.39
POLB P06746 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18224251 0.89 CSNK2A1 (0.59) CSNK2A1HDAC7MEN1KMT2APPARG
SCHEMBL2373875 0.85 ALDH1A1 (0.52) CSNK2A1HDAC7MEN1KMT2ANFE2L2
SCHEMBL26740880 0.84 CYP46A1 (0.51) RAB9ANPC1KDM4EHPGDLMNA
SCHEMBL1311663 0.84 MEN1 (0.53) CSNK2A1MEN1KMT2ARAB9ANPC1
SCHEMBL108320 0.84 NFE2L2 (0.47) CSNK2A1MEN1KMT2ANFE2L2RAB9A
SCHEMBL670210 0.82 HPGD (0.51) MEN1KMT2APPARGPPARARAB9A
SCHEMBL1890589 0.82 NPC1 (0.53) CSNK2A1RAB9ANPC1KDM4EHPGD
SCHEMBL5958350 0.82 CSNK2A1 (0.67) CSNK2A1MEN1KMT2ARAB9ANPC1
SCHEMBL1489033 0.82 RAB9A (0.47) CSNK2A1MEN1KMT2APPARGPPARA
SCHEMBL5484397 0.81 AKR1C3 (0.54) MEN1KMT2ANFE2L2NPC1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102030843-B Non-metallocene catalyst system for olefin polymerization and preparation and application thereof PETROCHINA CO LTD 2012-05-30 CN disclosed
EP-2070975-B1 POROUS FILM AND SEPARATOR FOR NONAQUEOUS ELECTROLYTE SECONDARY BATTERY SUMITOMO CHEMICAL CO (JP) 2012-01-25 EP disclosed
EP-2067618-B1 MULTILAYER POROUS FILM AND SEPARATOR FOR NONAQUEOUS ELECTROLYTE SECONDARY BATTERY SUMITOMO CHEMICAL CO (JP) 2012-01-11 EP disclosed
CN-102030843-A Non-metallocene catalyst system for olefin polymerization and preparation and application thereof PETROCHINA CO LTD 2011-04-27 CN disclosed
US-20100040953-A1 POROUS FILM AND SEPARATOR FOR NONAQUEOUS ELECTROLYTE SECONDARY BATTERY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-18 US disclosed
US-20100015515-A1 LAMINATED POROUS FILM AND SEPARATOR FOR NONAQUEOUS ELECTROLYTE SECONDARY BATTERY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-01-21 US disclosed
EP-2070975-A1 POROUS FILM AND SEPARATOR FOR NONAQUEOUS ELECTROLYTE SECONDARY BATTERY Sumitomo Chemical Company, Limited (JP) 2009-06-17 EP disclosed
EP-2067618-A1 MULTILAYER POROUS FILM AND SEPARATOR FOR NONAQUEOUS ELECTROLYTE SECONDARY BATTERY Sumitomo Chemical Company, Limited (JP) 2009-06-10 EP disclosed
US-20060234031-A1 Porous film, and production method and applications thereof SUMITOMO CHEMICAL COMPANY, LIMITED 2006-10-19 US disclosed