SCHEMBL987343

SCHEMBL987343

CC(C)(Oc1ccc(Oc2ccc(Cl)cc2Cl)cc1)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 10/20 0.67
MEN1 O00255 1/20 0.67
CYP1A2 P05177 1/20 0.67
CYP3A4 P08684 1/20 0.67
CYP2D6 P10635 1/20 0.67
MAPT P10636 1/20 0.67
CYP2C19 P33261 1/20 0.67
KMT2A Q03164 1/20 0.67
PPARG P37231 7/20 0.58
FABP2 P12104 2/20 0.58
SLC22A12 Q96S37 1/20 0.58
PPARD Q03181 6/20 0.56
FFAR1 O14842 2/20 0.56
MRGPRX4 Q96LA9 1/20 0.51
PDE5A O76074 1/20 0.47
MAP4K4 O95819 1/20 0.47
KCNH2 Q12809 1/20 0.47
MINK1 Q8N4C8 1/20 0.47
TTR P02766 1/20 0.47
ALDH1A1 P00352 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,4-Dichlorophenoxyacetic Acid SCHEMBL9376023 0.90 TDP1 (0.63) PPARAMEN1CYP1A2CYP3A4CYP2D6
Diclofop SCHEMBL11459120 0.89 PPARA (0.53) PPARAMEN1CYP1A2CYP3A4CYP2D6
Chloramben SCHEMBL8309339 0.85 ALDH1A1 (0.49) PPARAMEN1CYP1A2CYP3A4CYP2D6
SCHEMBL581884 0.85 PPARA (0.59) PPARAMEN1CYP1A2CYP3A4CYP2D6
SCHEMBL11213612 0.84 FFAR1 (0.61) PPARAMEN1CYP1A2CYP3A4CYP2D6
SCHEMBL11465749 0.84 FFAR1 (0.54) PPARAMEN1CYP1A2CYP3A4CYP2D6
SCHEMBL9853190 0.84 PSEN1 (0.48) PPARAMEN1CYP1A2CYP3A4CYP2D6
SCHEMBL9320807 0.83 PPARA (0.89) PPARAMEN1CYP1A2CYP3A4CYP2D6
SCHEMBL11342039 0.83 PPARA (0.49) PPARAMEN1CYP1A2CYP3A4CYP2D6
Metaxon SCHEMBL11008133 0.83 TDP1 (0.53) PPARAMEN1CYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2836072-B1 HERBICIDAL COMPOSITION COMPRISING AN URACIL COMPOUND AS ACTIVE INGREDIENT DONGBU FARM HANNONG CO LTD (KR) 2018-11-21 EP claimed
EP-2836072-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT Dongbu Farm Hannong Co., Ltd. (KR) 2015-02-18 EP claimed
US-20150024940-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT DONGBU FARM HANNONG CO., LTD. (KR) 2015-01-22 US claimed
WO-2013154396-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT DONGBU FARM HANNONG CO., LTD. (KR) 2013-10-17 WO claimed
US-6849578-B1 Selective herbicides based on 2,6-disubstituted pyridine derivatives BAYER AKTIENGESELLSCHAFT (DE) 2005-02-01 US claimed
EP-1453377-A1 HERBICIDES BASED ON SUBSTITUTED CARBOXYLIC ACID ANILIDES Bayer CropScience AG (DE) 2004-09-08 EP claimed
US-20040171488-A1 N-aryl-uracils based Herbicides FEUCHT DIETER (DE) 2004-09-02 US claimed
EP-1429612-A1 HERBICIDES CONTAINING SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONE Bayer CropScience AG (DE) 2004-06-23 EP claimed
EP-1423009-A2 HERBICIDES MADE FROM SUBSTITUTED ARYL KETONES Bayer CropScience AG (DE) 2004-06-02 EP claimed
EP-0901753-B1 HERBICIDAL COMPOSITION UBE INDUSTRIES (JP) 2004-04-28 EP claimed
WO-2001035741-A2 SYNERGISTIC HERBICIDAL ACTIVE SUBSTANCE COMBINATIONS BAYER AKTIENGESELLSCHAFT (DE) 2001-05-25 WO claimed
WO-2001024633-A2 SELECTIVE HERBICIDES BASED ON PYRIMIDINE-DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2001-04-12 WO claimed
WO-2001022819-A1 SELECTIVE HERBICIDES ON THE BASIS OF N-ARYL-TRIAZOLINE(THI)ONES BAYER AKTIENGESELLSCHAFT (DE) 2001-04-05 WO claimed
EP-0929221-A1 SELECTIVE HERBICIDES BASED ON ARYLSULPHONYLAMINOCARBONYLTRIAZOLINONES BAYER AG (DE) 1999-07-21 EP claimed
WO-1998012923-A1 SELECTIVE HERBICIDES BASED ON ARYLSULPHONYLAMINOCARBONYLTRIAZOLINONES BAYER AKTIENGESELLSCHAFT (DE) 1998-04-02 WO claimed
EP-0613618-B1 Method for safening herbicides in crops using substituted benzopyran and tetrahydronaphthalene compounds AMERICAN CYANAMID CO (US) 1997-04-16 EP claimed
EP-0496608-B1 Substituted pyridinesulfonamide compound or its salt, process for preparing the same, and herbicide containing the same ISHIHARA SANGYO KAISHA (JP) 1995-09-20 EP claimed
EP-0212200-B1 PYRIDINE DERIVATIVES AND HERBICIDAL COMPOSITION NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1993-03-24 EP claimed
EP-0212200-A2 Pyridine derivatives and herbicidal composition NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1987-03-04 EP claimed
EP-0049397-A1 A herbicidal composition AMERICAN HOECHST CORPORATION (US) 1982-04-14 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150024940-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT UNG, DDT, HDHD5 PPARA 2744/4885MEN1 4570/4885CYP1A2 2455/4885
US-20040171488-A1 N-aryl-uracils based Herbicides DDT, UNG, DDC PPARA 1650/4885MEN1 4777/4885CYP1A2 377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.