Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | FABP4 | P15090 | 1/20 | 0.52 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | CD40 | P25942 | 3/20 | 0.49 |
| ▸ | CD40LG | P29965 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | PLEC | Q15149 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6242038 | 0.81 | CD40 (0.61) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL11759224 | 0.75 | TTR (0.59) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL14058895 | 0.73 | CD40 (0.56) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL26885009 | 0.72 | TTR (0.56) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL1044488 | 0.72 | HSD17B10 (0.52) | HSD17B10CA1CA2TDP1MPL | |
| SCHEMBL3417435 | 0.71 | PTPN1 (0.53) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL19020654 | 0.71 | CD40 (0.69) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL11511725 | 0.71 | CD40 (0.69) | CD40CD40LGMEN1KMT2AMAPT | |
| SCHEMBL23796458 | 0.70 | CA1 (0.45) | HSD17B10MEN1KMT2APKMMAPT | |
| SCHEMBL30031321 | 0.70 | CA1 (0.45) | HSD17B10MEN1KMT2APKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008154-A1 | Ureylene phenylene anionic naphthalene-sulfonic acids, their use as complement system inhibitors in a body fluid and process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1980-02-20 | — | — | EP | claimed |
| EP-0008154-A1 | Ureylene phenylene anionic naphthalene-sulfonic acids, their use as complement system inhibitors in a body fluid and process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1980-02-20 | — | — | EP | disclosed |