Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 4/20 | 0.31 |
| ▸ | MAOA | P21397 | 4/20 | 0.31 |
| ▸ | MAOB | P27338 | 4/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11529077 | 0.87 | TSHR (0.35) | TSHRKMT2ACYP2D6LMNAKDM1A | |
| SCHEMBL11525444 | 0.87 | LMNA (0.36) | TSHRKMT2ACYP2D6LMNAKDM1A | |
| SCHEMBL11525955 | 0.85 | TSHR (0.34) | TSHRKMT2ACYP2D6LMNAKDM1A | |
| SCHEMBL11528520 | 0.85 | TSHR (0.34) | TSHRKMT2ACYP2D6LMNAKDM1A | |
| SCHEMBL28475755 | 0.83 | TSHR (0.33) | TSHRKMT2ACYP2D6LMNA | |
| SCHEMBL11526006 | 0.82 | EZH2 (0.34) | TSHRKMT2ACYP2D6LMNA | |
| SCHEMBL11525453 | 0.80 | KMT2A (0.42) | TSHRKMT2ACYP2D6LMNA | |
| SCHEMBL11526004 | 0.80 | CYP2D6 (0.36) | TSHRKMT2ACYP2D6LMNA | |
| SCHEMBL11523500 | 0.78 | GAA (0.50) | TSHRKMT2ALMNAKDM1A | |
| SCHEMBL11524877 | 0.76 | MAPT (0.39) | TSHRKMT2ACYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177186-A | 4-SILOXY-DERIVATIVES OF STERICALLY HINDERED PIPERIDINES | CIBA-GEIGY CORPORATION (US) | 1979-12-04 | — | — | US | claimed |
| US-4202816-A | ENOL-PIPERIDINE METAL COMPLEXES | CIBA-GEIGY CORPORATION (US) | 1980-05-13 | — | — | US | disclosed |
| US-4177186-A | 4-SILOXY-DERIVATIVES OF STERICALLY HINDERED PIPERIDINES | CIBA-GEIGY CORPORATION (US) | 1979-12-04 | — | — | US | disclosed |