Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11467386 | 0.82 | TSHR (0.35) | TSHRKMT2ACYP2D6LMNA | |
| SCHEMBL11526004 | 0.76 | CYP2D6 (0.36) | TSHRKMT2ACYP2D6LMNA | |
| SCHEMBL11525453 | 0.76 | KMT2A (0.42) | TSHRKMT2ACYP2D6LMNAMAPK1 | |
| SCHEMBL11524877 | 0.75 | MAPT (0.39) | TSHRKMT2ACYP2D6LMNA | |
| SCHEMBL11524799 | 0.74 | UBE2M (0.36) | TSHRLMNAMAPK1 | |
| SCHEMBL9461585 | 0.72 | KMT2A (0.39) | EZH2KMT2ACYP2D6LMNA | |
| SCHEMBL11523500 | 0.71 | GAA (0.50) | EZH2TSHRKMT2ALMNA | |
| SCHEMBL11527520 | 0.70 | OPRK1 (0.38) | TSHRKMT2A | |
| SCHEMBL11171981 | 0.70 | — | — | |
| SCHEMBL11529077 | 0.70 | TSHR (0.35) | TSHRKMT2ACYP2D6LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177186-A | 4-SILOXY-DERIVATIVES OF STERICALLY HINDERED PIPERIDINES | CIBA-GEIGY CORPORATION (US) | 1979-12-04 | — | — | US | disclosed |