Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11467386 | 0.80 | TSHR (0.35) | CYP2D6LMNATSHRKMT2A | |
| SCHEMBL11525453 | 0.77 | KMT2A (0.42) | CYP2D6LMNATSHRKMT2A | |
| SCHEMBL11526006 | 0.76 | EZH2 (0.34) | CYP2D6LMNATSHRKMT2A | |
| SCHEMBL11524877 | 0.73 | MAPT (0.39) | CYP2D6LMNATSHRKMT2A | |
| SCHEMBL11523500 | 0.72 | GAA (0.50) | LMNATSHRKMT2A | |
| SCHEMBL11529077 | 0.68 | TSHR (0.35) | CYP2D6LMNATSHRKMT2A | |
| SCHEMBL11525444 | 0.68 | LMNA (0.36) | CYP2D6LMNATSHRKMT2A | |
| SCHEMBL11528520 | 0.67 | TSHR (0.34) | CYP2D6LMNATSHRKMT2A | |
| SCHEMBL11525955 | 0.67 | TSHR (0.34) | CYP2D6LMNATSHRKMT2A | |
| SCHEMBL11528307 | 0.66 | TSHR (0.45) | CYP2D6LMNATSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177186-A | 4-SILOXY-DERIVATIVES OF STERICALLY HINDERED PIPERIDINES | CIBA-GEIGY CORPORATION (US) | 1979-12-04 | — | — | US | disclosed |