Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.65 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68390 | 0.89 | SRD5A2 (0.69) | TSHRALOX15ALDH1A1SRD5A2TP53 | |
| SCHEMBL5751057 | 0.87 | TSHR (0.74) | TSHRALOX15ALDH1A1SRD5A2NR4A2 | |
| Hydrochloric Acid SCHEMBL25188150 | 0.86 | SRD5A2 (0.67) | TSHRALOX15ALDH1A1SRD5A2TP53 | |
| Hydrochloric Acid SCHEMBL7133360 | 0.86 | SRD5A2 (0.67) | TSHRALOX15ALDH1A1SRD5A2TP53 | |
| 4-Chloro-Benzoic Acid SCHEMBL28384 | 0.86 | TSHR (1.00) | TSHRALOX15ALDH1A1SRD5A2NR4A2 | |
| 4-Chloro-Benzoic Acid SCHEMBL1331727 | 0.86 | TSHR (1.00) | TSHRALOX15ALDH1A1SRD5A2NR4A2 | |
| SCHEMBL28129556 | 0.86 | ALOX15 (0.54) | TSHRALOX15ALDH1A1SRD5A2NR4A2 | |
| SCHEMBL9065883 | 0.84 | SRD5A2 (0.61) | TSHRALOX15ALDH1A1SRD5A2KMT2A | |
| SCHEMBL11464002 | 0.84 | SRD5A2 (0.61) | TSHRALOX15ALDH1A1SRD5A2KMT2A | |
| 4-Chloro-Benzoic Acid SCHEMBL2918294 | 0.84 | TSHR (0.94) | TSHRALOX15ALDH1A1SRD5A2NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0016703-A1 | Lysine salt of (+/-) 3-amino-4-(1-pyrrolyl)-alpha-methylphenyl-acetic acid, process for its preparation and pharmaceutical composition containing it | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1980-10-01 | — | — | EP | disclosed |
| US-4208425-A | VIRICIDES | STERLING DRUG INC. (US) | 1980-06-17 | — | — | US | disclosed |
| US-4153719-A | Aromatic diketones | STERLING DRUG INC. (US) | 1979-05-08 | — | — | US | disclosed |