Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 10/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11247874 | 0.86 | CACNA2D1 (0.55) | CACNA2D1MAPTTP53MEN1KMT2A | |
| SCHEMBL11240195 | 0.82 | CACNA2D1 (0.49) | CACNA2D1MAPTTP53ALDH1A1 | |
| SCHEMBL11743527 | 0.80 | MAPT (0.38) | CACNA2D1MAPTTP53MEN1KMT2A | |
| SCHEMBL8463737 | 0.78 | NQO1 (0.58) | MAPTLMNAALDH1A1NPSR1 | |
| SCHEMBL11469647 | 0.76 | PTGES (0.39) | MAPTTP53LMNAALDH1A1 | |
| SCHEMBL11751925 | 0.76 | CACNA2D1 (0.47) | CACNA2D1MAPTTP53MEN1KMT2A | |
| SCHEMBL11474951 | 0.74 | GPR84 (0.44) | ALDH1A1 | |
| SCHEMBL11477369 | 0.74 | CACNA2D1 (0.45) | CACNA2D1MAPTTP53MEN1KMT2A | |
| SCHEMBL11477306 | 0.74 | GPR84 (0.51) | CACNA2D1MAPTTP53MEN1KMT2A | |
| SCHEMBL11483156 | 0.73 | PTGES (0.49) | CACNA2D1MAPTTP53LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190725-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4021553-A | 5,6-Diaryl-1,2,4-triazines as topically-active anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1977-05-03 | — | — | US | disclosed |