Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | TP53 | P04637 | 5/20 | 0.48 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11470583 | 0.88 | GPR84 (0.65) | GPR84MAPTTP53CACNA2D1NQO1 | |
| SCHEMBL11241755 | 0.87 | CACNA2D1 (0.47) | GPR84MAPTTP53CACNA2D1NQO1 | |
| SCHEMBL11468338 | 0.86 | PTGES (0.53) | GPR84MAPTL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL11485851 | 0.84 | TP53 (0.54) | GPR84MAPTTP53CACNA2D1RAB9A | |
| SCHEMBL11484157 | 0.80 | LMNA (0.49) | GPR84MAPTTP53CACNA2D1ALDH1A1 | |
| SCHEMBL11247874 | 0.79 | CACNA2D1 (0.55) | MAPTTP53CACNA2D1NQO1RAB9A | |
| SCHEMBL13108709 | 0.79 | ALDH1A1 (0.53) | MAPTTP53CACNA2D1NQO1RAB9A | |
| SCHEMBL11483014 | 0.79 | NQO1 (0.48) | MAPTTP53CACNA2D1NQO1RAB9A | |
| SCHEMBL11483085 | 0.78 | ACACB (0.47) | GPR84MAPTTP53CACNA2D1RAB9A | |
| SCHEMBL11863432 | 0.78 | CACNA2D1 (0.48) | MAPTTP53CACNA2D1NQO1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190725-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4021553-A | 5,6-Diaryl-1,2,4-triazines as topically-active anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1977-05-03 | — | — | US | disclosed |