Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.59 |
| ▸ | PTGES | O14684 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11476538 | 0.81 | TP53 (0.62) | TP53PTGESMAPTGAAMGAM | |
| SCHEMBL11479740 | 0.78 | PTGES (0.73) | TP53PTGESMAPTPTGS2LMNA | |
| SCHEMBL11244831 | 0.77 | PTGES (0.80) | TP53PTGESMAPTGAAMGAM | |
| SCHEMBL11240834 | 0.74 | PTGES (0.90) | TP53PTGESMAPTGAAMGAM | |
| SCHEMBL11485855 | 0.74 | KCNH2 (0.41) | TP53MAPTGAAALDH1A1LMNA | |
| SCHEMBL11477195 | 0.74 | TP53 (0.55) | TP53PTGESMAPTGAAMGAM | |
| SCHEMBL11231108 | 0.74 | PTGES (0.71) | TP53PTGESMAPTGAAMGAM | |
| SCHEMBL11243005 | 0.74 | NPSR1 (0.58) | TP53PTGESMAPTKDM4EALDH1A1 | |
| SCHEMBL11477119 | 0.72 | PTGES (1.00) | TP53PTGESMAPTPTGS2 | |
| SCHEMBL11467233 | 0.72 | PTGES (0.71) | TP53PTGESMAPTGAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190725-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1980-02-26 | — | — | US | disclosed |