Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | PTGES | O14684 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAPDH | P04406 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11467226 | 0.88 | NPSR1 (0.47) | NPSR1PTGESMAPTLMNAALDH1A1 | |
| SCHEMBL11240864 | 0.82 | NPSR1 (0.64) | NPSR1PTGESMAPTLMNAALDH1A1 | |
| SCHEMBL11470501 | 0.79 | MAPT (0.40) | MAPTALDH1A1TP53MCL1KMT2A | |
| SCHEMBL11479740 | 0.78 | PTGES (0.73) | PTGESMAPTLMNATP53 | |
| SCHEMBL11477773 | 0.78 | NPSR1 (0.58) | NPSR1PTGESMAPTLMNASMN1; SMN2 | |
| SCHEMBL11873100 | 0.78 | MAP4K4 (0.40) | MAPTTP53MCL1KMT2ANOTUM | |
| SCHEMBL11476429 | 0.77 | TP53 (0.39) | NPSR1PTGESMAPTLMNAALDH1A1 | |
| SCHEMBL11719116 | 0.77 | NPSR1 (0.57) | NPSR1PTGESMAPTTP53MEN1 | |
| SCHEMBL10812615 | 0.76 | NPSR1 (0.70) | NPSR1MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11747087 | 0.76 | NPSR1 (0.70) | NPSR1PTGESMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4318911-A | 5,6-Diaryl-1,2,4-triazines as topical antithrombotic agents | ELI LILLY AND COMPANY (US) | 1982-03-09 | — | — | US | disclosed |
| US-4190725-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4021553-A | 5,6-Diaryl-1,2,4-triazines as topically-active anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1977-05-03 | — | — | US | disclosed |