Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 5/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11613328 | 0.79 | CTRB1 (0.32) | CTRB1 | |
| SCHEMBL11460605 | 0.74 | HRH4 (0.51) | — | |
| SCHEMBL19882987 | 0.71 | DPP4 (0.48) | CTRB1DPP8DPP7 | |
| SCHEMBL10937092 | 0.65 | HRH1 (0.41) | CTRB1 | |
| SCHEMBL14037799 | 0.64 | — | — | |
| SCHEMBL11192511 | 0.64 | DPP4 (0.41) | CTRB1DPP8DPP7 | |
| SCHEMBL10921826 | 0.61 | BRS3 (0.35) | — | |
| SCHEMBL7484552 | 0.61 | GLA (0.39) | — | |
| Bromide SCHEMBL11534772 | 0.61 | DPP7 (0.41) | CTRB1DPP8DPP7 | |
| SCHEMBL31022920 | 0.60 | HTT (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4221914-A | ANTIHISTAMINES, HISTIDINE DECARBOXYLASE INHIBITORS | MERRELL TORAUDE ET COMPAGNIE (FR) | 1980-09-09 | — | — | US | disclosed |