SCHEMBL11468151

SCHEMBL11468151

Oc1cc(OCCBr)ccc1-n1nnc2ccccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNMA1 Q12791 2/20 0.55
RAB9A P51151 3/20 0.46
NPC1 O15118 1/20 0.46
KMT2A Q03164 5/20 0.40
MEN1 O00255 3/20 0.40
POLB P06746 2/20 0.40
MGAM O43451 1/20 0.40
AMY1A P0DUB6 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
MAPT P10636 3/20 0.38
HSD17B10 Q99714 2/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
LMNA P02545 3/20 0.36
ALDH1A1 P00352 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
BRD4 O60885 1/20 0.36
KDM4E B2RXH2 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8049206 0.85 KCNMA1 (0.51) KCNMA1RAB9ANPC1MGAMAMY1A
SCHEMBL15766018 0.82 KCNMA1 (0.53) KCNMA1RAB9ANPC1KMT2AMEN1
SCHEMBL7267371 0.80 THRB (0.48) KCNMA1RAB9ANPC1KMT2AMEN1
SCHEMBL9801804 0.79 KCNMA1 (0.71) KCNMA1RAB9AKMT2AMEN1POLB
SCHEMBL3974127 0.78 KCNMA1 (0.57) KCNMA1RAB9ANPC1KMT2AMEN1
SCHEMBL8645601 0.73 KCNMA1 (0.67) KCNMA1RAB9ANPC1KMT2APOLB
SCHEMBL15765998 0.73 KCNMA1 (0.48) KCNMA1RAB9ANPC1KMT2AMEN1
SCHEMBL80393 0.72 KCNMA1 (1.00) KCNMA1RAB9AKMT2AMEN1POLB
SCHEMBL3901060 0.71 KCNMA1 (0.45) KCNMA1RAB9ANPC1KMT2AMEN1
SCHEMBL11521392 0.70 KCNMA1 (0.61) KCNMA1RAB9AKMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4187229-A Bis-benzotriazole compounds EASTMAN KODAK COMPANY (US) 1980-02-05 US disclosed
US-4085089-A Benzotriazole ultraviolet stabilizing compounds and their use in organic compositions EASTMAN KODAK COMPANY (US) 1978-04-18 US disclosed