Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.36 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11471160 | 0.94 | LMNA (0.51) | LMNAGAAALDH1A1MAPTMEN1 | |
| SCHEMBL11470726 | 0.81 | TP53 (0.50) | LMNACYP1A2GAAALDH1A1MAPT | |
| SCHEMBL11469963 | 0.81 | GAA (0.48) | CYP1A2CYP2D6GAAALDH1A1MAPT | |
| SCHEMBL11483171 | 0.79 | RAB9A (0.49) | LMNACYP1A2CYP2D6CYP2C19GAA | |
| SCHEMBL11475908 | 0.76 | RAB9A (0.47) | CYP1A2CYP2D6CYP2C19GAAALDH1A1 | |
| SCHEMBL11467362 | 0.76 | CYP1A2 (0.45) | LMNACYP1A2CYP2D6CYP2C19GAA | |
| SCHEMBL11483014 | 0.76 | NQO1 (0.48) | LMNACYP1A2CYP2D6CYP2C19GAA | |
| SCHEMBL11240195 | 0.75 | CACNA2D1 (0.49) | CYP1A2GAAALDH1A1MAPTTP53 | |
| SCHEMBL11468991 | 0.73 | WDR5 (0.37) | LMNAALDH1A1MAPTNPSR1TP53 | |
| SCHEMBL11469872 | 0.73 | CACNA2D1 (0.48) | LMNAGAAALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190725-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4021553-A | 5,6-Diaryl-1,2,4-triazines as topically-active anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1977-05-03 | — | — | US | disclosed |