Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ADK | P55263 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11470140 | 0.93 | TLR7 (0.43) | MAPTADKHSD17B10KDM4EALDH1A1 | |
| SCHEMBL11244627 | 0.88 | ADK (0.38) | MAPTADKHSD17B10KDM4EALDH1A1 | |
| SCHEMBL11467948 | 0.87 | PTGES (0.35) | MAPTHSD17B10KDM4EALDH1A1RAB9A | |
| SCHEMBL11483171 | 0.83 | RAB9A (0.49) | MAPTHSD17B10KDM4EALDH1A1RAB9A | |
| SCHEMBL11485177 | 0.82 | ADK (0.37) | ADKTLR7NOX1SYKTP53 | |
| SCHEMBL11470726 | 0.81 | TP53 (0.50) | MAPTHSD17B10KDM4EALDH1A1RAB9A | |
| SCHEMBL11485833 | 0.81 | PTGES (0.51) | MAPTHSD17B10KDM4EALDH1A1RAB9A | |
| SCHEMBL11485810 | 0.80 | MAPT (0.45) | MAPTADKHSD17B10KDM4EALDH1A1 | |
| SCHEMBL11469809 | 0.79 | CNR1 (0.47) | MAPTADKHSD17B10KDM4EALDH1A1 | |
| SCHEMBL11469647 | 0.79 | PTGES (0.39) | MAPTHSD17B10KDM4EALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190725-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4021553-A | 5,6-Diaryl-1,2,4-triazines as topically-active anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1977-05-03 | — | — | US | disclosed |