Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | ADK | P55263 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11709965 | 0.82 | MAPT (0.36) | ADKALDH1A1LMNANPSR1MAPT | |
| SCHEMBL11244627 | 0.81 | ADK (0.38) | ADKALDH1A1NOX1HTTNPSR1 | |
| SCHEMBL11468702 | 0.81 | TP53 (0.49) | ALDH1A1LMNAHTTNPSR1MAPT | |
| SCHEMBL11468266 | 0.79 | MAPT (0.36) | ADKALDH1A1NOX1MAPTHPGD | |
| SCHEMBL11470140 | 0.78 | TLR7 (0.43) | ADKALDH1A1MAPTHPGDCYP3A4 | |
| SCHEMBL11485810 | 0.76 | MAPT (0.45) | ADKALDH1A1NOX1MAPTHPGD | |
| SCHEMBL11485177 | 0.74 | ADK (0.37) | ADKNOX1NPSR1CYP1A2CYP2C19 | |
| SCHEMBL11468308 | 0.73 | CYP1A2 (0.37) | ADKALDH1A1NOX1LMNAMAPT | |
| SCHEMBL31582507 | 0.71 | HTR7 (0.49) | ALDH1A1LMNAHTTNPSR1MAPT | |
| SCHEMBL11273639 | 0.71 | GPR84 (0.49) | ALDH1A1LMNANPSR1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190725-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4021553-A | 5,6-Diaryl-1,2,4-triazines as topically-active anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1977-05-03 | — | — | US | disclosed |