Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11477154 | 0.88 | GPR84 (0.67) | PTGESGPR84MAPTALDH1A1KDM4E | |
| SCHEMBL11231246 | 0.87 | GPR84 (0.54) | PTGESGPR84ALDH1A1KDM4ELMNA | |
| SCHEMBL11477306 | 0.86 | GPR84 (0.51) | GPR84MAPTALDH1A1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL9695495 | 0.84 | MAOB (0.53) | PTGESGPR84ALDH1A1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL9695587 | 0.81 | GPR84 (0.52) | PTGESGPR84ALDH1A1KDM4ELMNA | |
| SCHEMBL9696190 | 0.79 | GPR84 (0.51) | PTGESGPR84MAPTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9694156 | 0.78 | GPR84 (0.50) | PTGESGPR84MAPTALDH1A1KDM4E | |
| SCHEMBL11238109 | 0.78 | KDM4E (0.51) | PTGESGPR84MAPTALDH1A1KDM4E | |
| SCHEMBL11484072 | 0.77 | GPR84 (0.53) | PTGESGPR84MAPTALDH1A1KDM4E | |
| SCHEMBL11466772 | 0.77 | GPR84 (0.53) | GPR84MAPTALDH1A1KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190725-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4021553-A | 5,6-Diaryl-1,2,4-triazines as topically-active anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1977-05-03 | — | — | US | disclosed |