Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.51 |
| ▸ | PTGES | O14684 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9694156 | 0.98 | GPR84 (0.50) | GPR84PTGESALDH1A1KDM4ELMNA | |
| SCHEMBL11231246 | 0.82 | GPR84 (0.54) | GPR84PTGESALDH1A1KDM4ELMNA | |
| SCHEMBL11238109 | 0.80 | KDM4E (0.51) | GPR84PTGESALDH1A1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL9695587 | 0.79 | GPR84 (0.52) | GPR84PTGESALDH1A1KDM4ELMNA | |
| SCHEMBL11468338 | 0.79 | PTGES (0.53) | GPR84PTGESALDH1A1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL9695495 | 0.77 | MAOB (0.53) | GPR84PTGESALDH1A1KDM4ELMNA | |
| SCHEMBL11472295 | 0.76 | GPR84 (0.62) | GPR84PTGESALDH1A1KDM4ELMNA | |
| SCHEMBL11742743 | 0.76 | ALDH1A1 (0.49) | GPR84PTGESALDH1A1KDM4ELMNA | |
| SCHEMBL11477154 | 0.75 | GPR84 (0.67) | GPR84PTGESALDH1A1KDM4ELMNA | |
| SCHEMBL21852751 | 0.73 | ALDH1A1 (0.67) | ALDH1A1KDM4ELMNANPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002513-A1 | HETEROCYCLIC COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-02-20 | — | — | WO | disclosed |