Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 7/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 7/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL11470262 | 0.98 | KDM2B (0.44) | OPRL1KDM2BMMP2MMP9OPRM1 | |
| SCHEMBL11478230 | 0.95 | OPRL1 (0.48) | OPRL1OPRM1OPRK1SIGMAR1 | |
| SCHEMBL11470563 | 0.89 | OPRL1 (0.43) | OPRL1KDM2BMMP2MMP9OPRM1 | |
| Oxalic Acid SCHEMBL11486423 | 0.87 | KDM2B (0.43) | OPRL1KDM2BMMP2MMP9OPRM1 | |
| SCHEMBL11486582 | 0.87 | OPRM1 (0.52) | OPRM1OPRK1 | |
| Bromide SCHEMBL11472634 | 0.86 | OPRM1 (0.51) | OPRM1OPRK1 | |
| SCHEMBL11468585 | 0.86 | OPRK1 (0.51) | OPRL1OPRM1OPRK1 | |
| SCHEMBL11468367 | 0.82 | SCN1A (0.48) | OPRL1OPRM1OPRK1SIGMAR1 | |
| Oxalic Acid SCHEMBL11468650 | 0.80 | SCN1A (0.46) | OPRL1OPRM1OPRK1SIGMAR1 | |
| SCHEMBL11470298 | 0.78 | OTUD7B (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4198417-A | ANALGESICS, ANTIDEPRESSANTS, ANTICONVULSANTS | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | claimed |