Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 4/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.51 |
| ▸ | CCR8 | P51685 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11479599 | 0.89 | OPRK1 (0.50) | OPRK1OPRM1OPRD1CCR8ALDH1A1 | |
| SCHEMBL11468366 | 0.86 | OPRL1 (0.44) | OPRK1OPRM1OPRL1 | |
| SCHEMBL11468367 | 0.86 | SCN1A (0.48) | OPRK1OPRM1OPRD1ALDH1A1GAA | |
| Oxalic Acid SCHEMBL11470262 | 0.84 | KDM2B (0.44) | OPRK1OPRM1OPRL1 | |
| Oxalic Acid SCHEMBL11468650 | 0.84 | SCN1A (0.46) | OPRK1OPRM1OPRD1ALDH1A1KDM4E | |
| SCHEMBL11478230 | 0.83 | OPRL1 (0.48) | OPRK1OPRM1OPRD1OPRL1 | |
| SCHEMBL11470298 | 0.81 | OTUD7B (0.47) | ALDH1A1GAATSHRRECQLLMNA | |
| SCHEMBL11470732 | 0.81 | SLC18A3 (0.51) | ALDH1A1 | |
| SCHEMBL11477208 | 0.79 | SIGMAR1 (0.44) | OPRM1CCR8KCNH2 | |
| SCHEMBL11479586 | 0.78 | SLC18A3 (0.56) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4198417-A | ANALGESICS, ANTIDEPRESSANTS, ANTICONVULSANTS | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |