SCHEMBL11468369

SCHEMBL11468369

Cc1ccc(NC([O])=O)cc1NC([O])=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.53
ALDH1A1 P00352 6/20 0.53
KMT2A Q03164 5/20 0.50
LMNA P02545 3/20 0.50
MEN1 O00255 2/20 0.50
ATM Q13315 1/20 0.50
NPC1 O15118 4/20 0.49
RAB9A P51151 3/20 0.49
NPSR1 Q6W5P4 2/20 0.49
RXFP1 Q9HBX9 1/20 0.49
POLB P06746 2/20 0.48
MAPK1 P28482 1/20 0.46
DDX3X O00571 1/20 0.43
HTT P42858 1/20 0.42
KDM4E B2RXH2 1/20 0.42
RAF1 P04049 1/20 0.42
TP53 P04637 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30050717 0.82 MAPT (0.55) MAPTALDH1A1KMT2ALMNAMEN1
SCHEMBL378893 0.82 MAPT (0.55) MAPTALDH1A1KMT2ALMNAMEN1
SCHEMBL31725340 0.80 KMT2A (0.65) MAPTALDH1A1KMT2ALMNAMEN1
SCHEMBL8716883 0.80 KMT2A (0.65) MAPTALDH1A1KMT2ALMNAMEN1
Hydrochloric Acid SCHEMBL11406931 0.80 MAPT (0.53) MAPTALDH1A1KMT2ALMNAMEN1
SCHEMBL1954485 0.78 KIF11 (0.52) MAPTALDH1A1KMT2ALMNAMEN1
SCHEMBL9220189 0.78 MAPT (0.51) MAPTALDH1A1KMT2ALMNAMEN1
SCHEMBL11508898 0.78 TGM2 (0.61) MAPTALDH1A1KMT2ALMNAMEN1
SCHEMBL12937737 0.77 KMT2A (0.57) MAPTALDH1A1KMT2ALMNAMEN1
SCHEMBL29922263 0.77 ALDH1A1 (0.57) MAPTALDH1A1KMT2ALMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4191574-A AZO-METHINE DYES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-03-04 US disclosed
US-4138264-A Silver halide emulsion containing two equivalent type coupler for use in photography KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1979-02-06 US disclosed