Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | DDX3X | O00571 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30050717 | 1.00 | MAPT (0.55) | MAPTALDH1A1NPC1RAB9ANPSR1 | |
| Hydrochloric Acid SCHEMBL11406931 | 0.98 | MAPT (0.53) | MAPTALDH1A1NPC1RAB9ANPSR1 | |
| SCHEMBL12937737 | 0.90 | KMT2A (0.57) | MAPTALDH1A1NPC1RAB9ANPSR1 | |
| SCHEMBL31267143 | 0.87 | HPGD (0.51) | MAPTALDH1A1NPC1RAB9ANPSR1 | |
| SCHEMBL18209634 | 0.87 | HPGD (0.51) | MAPTALDH1A1NPC1RAB9ANPSR1 | |
| SCHEMBL22210642 | 0.86 | RAB9A (0.51) | MAPTALDH1A1NPC1RAB9ANPSR1 | |
| SCHEMBL9926717 | 0.83 | NPC1 (0.44) | MAPTALDH1A1NPC1RAB9ANPSR1 | |
| SCHEMBL7563975 | 0.83 | NLRP3 (0.58) | MAPTALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL3012871 | 0.83 | POLB (0.70) | MAPTALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL4299638 | 0.82 | POLB (0.49) | MAPTALDH1A1NPC1RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023161645-A2 | PHARMACEUTICAL COMPOSITIONS FOR VAPORIZATION AND INHALATION | GROW BIOTECH PLC (GB) | 2023-08-31 | — | — | WO | claimed |
| CN-113024418-B | Method for synthesizing alicyclic carbamate by using isopropanol as hydrogen source | 河北工业大学 | 2023-01-24 | — | — | CN | claimed |
| EP-3630717-B1 | A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES | COUNCIL SCIENT IND RES (IN) | 2022-02-09 | — | — | EP | claimed |
| EP-2592069-B1 | METHOD OF PRODUCING TOLUENEDICARBAMATE AND METHOD OF PRODUCING TOLUENEDIISOCYANATE | MITSUI CHEMICALS INC (JP) | 2019-04-24 | — | — | EP | claimed |
| US-8742164-B2 | Method for producing toluenedicarbamate, method for producing toluenediisocyanate, and toluenedicarbamate | MITSUI CHEMICALS, INC. (JP) | 2014-06-03 | — | — | US | claimed |
| US-20140087207-A1 | ARTICLES COMPRISING A WEATHER-RESISTANT ADHESIVE LAYER IN CONTACT WITH A LOW SURFACE-ENERGY MATERIAL | DU PONT (US) | 2014-03-27 | — | — | US | claimed |
| EP-2592069-A1 | METHOD OF PRODUCING TOLUENEDICARBAMATE, METHOD OF PRODUCING TOLUENEDIISOCYANATE, AND TOLUENEDICARBAMATE | Mitsui Chemicals, Inc. (JP) | 2013-05-15 | — | — | EP | claimed |
| US-20130109881-A1 | METHOD FOR PRODUCING TOLUENEDICARBAMATE, METHOD FOR PRODUCING TOLUENEDIISOCYANATE, AND TOLUENEDICARBAMATE | MITSUI CHEMICALS, INC. | 2013-05-02 | — | — | US | claimed |
| EP-1420013-B1 | Process for hydrogenating aromatic urethanes in the presence of a supported ruthenium catalyst | EVONIK DEGUSSA GMBH (DE) | 2008-04-02 | — | — | EP | claimed |
| EP-1420012-B1 | Process for the preparation of aliphatic isocyanates from aromatic isocyanates | DEGUSSA (DE) | 2006-11-02 | — | — | EP | claimed |
| EP-1362901-B1 | Thermoset adhesive films | NAT STARCH CHEM INVEST (US) | 2006-03-15 | — | — | EP | claimed |
| US-20050137340-A1 | Thermoset adhesive films | NIKOLIC NIKOLA A (US) | 2005-06-23 | — | — | US | claimed |
| EP-1420012-A1 | Process for the preparation of aliphatic isocyanates from aromatic isocyanates | Degussa AG (DE) | 2004-05-19 | — | — | EP | claimed |
| EP-1420013-A1 | Process for hydrogenating aromatic urethanes in the presence of a supported ruthenium catalyst | Degussa AG (DE) | 2004-05-19 | — | — | EP | claimed |
| EP-1362901-A2 | Thermoset adhesive films | National Starch and Chemical Investment Holding Corporation (US) | 2003-11-19 | — | — | EP | claimed |
| US-4081472-A | CATALYTIC, FROM A CARBAMATE | MITSUI TOATSU CHEMICALS INC. (JA) | 1978-03-28 | — | — | US | claimed |
| US-3962302-A | Production of isocyanates from esters of carbamic acids (urethanes) | ATLANTIC RICHFIELD COMPANY (US) | 1976-06-08 | — | — | US | claimed |
| CN-117866376-A | Polyacetal resin composition | 旭化成株式会社 | 2024-04-12 | — | — | CN | disclosed |
| US-3968092-A | Use of aromatic furfuryl polycarbamates as chloroprene polymer vulcanization accelerators | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-07-06 | — | — | US | disclosed |
| US-3962302-A | Production of isocyanates from esters of carbamic acids (urethanes) | ATLANTIC RICHFIELD COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109881-A1 | METHOD FOR PRODUCING TOLUENEDICARBAMATE, METHOD FOR PRODUCING TOLUENEDIISOCYANATE, AND TOLUENEDICARBAMATE | CPS1, TST, ALKBH3 | MAPT 1636/4885ALDH1A1 396/4885NPC1 2232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.