SCHEMBL1146837

SCHEMBL1146837

O=C(OC12CC3CC(CC(O)(C3)C1)C2)C(F)(F)S(=O)(=O)[O-].c1ccc([S+](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DPP8 Q6V1X1 1/20 0.33
DPP9 Q86TI2 1/20 0.33
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CYP17A1 P05093 1/20 0.32
CYP19A1 P11511 1/20 0.32
CNR2 P34972 1/20 0.31
DPP4 P27487 1/20 0.31
MDH1 P40925 1/20 0.31
MDH2 P40926 1/20 0.31
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
KDM4E B2RXH2 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30029494 0.83 SCN9A (0.37) DPP8DPP9ALDH1A1LMNAL3MBTL1
SCHEMBL525455 0.83 SCN9A (0.37) DPP8DPP9ALDH1A1LMNAL3MBTL1
SCHEMBL546868 0.82 TSHR (0.41) CYP17A1CYP19A1
SCHEMBL710675 0.81 CYP17A1 (0.34) CYP17A1CYP19A1
SCHEMBL32685241 0.80 ALDH1A1 (0.38) DPP8DPP9ALDH1A1LMNAL3MBTL1
SCHEMBL1146838 0.78 DPP8 (0.34) DPP8DPP9ALDH1A1LMNAL3MBTL1
SCHEMBL1635652 0.77 SCN9A (0.32)
SCHEMBL29721445 0.77 SCN9A (0.35) ALDH1A1L3MBTL1MDH1MDH2
SCHEMBL30361501 0.77 SCN9A (0.34) L3MBTL1
SCHEMBL1635900 0.77 SCN9A (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2293143-B1 Novel photoresist compositions ROHM & HAAS ELECT MAT (US) 2015-09-02 EP disclosed
EP-2293143-A2 Novel resins and photoresist compositions comprising the same Rohm and Haas Electronic Materials, L.L.C. (US) 2011-03-09 EP disclosed
US-20110039206-A1 NOVEL RESINS AND PHOTORESIST COMPOSITIONS COMPRISING SAME ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2011-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110039206-A1 NOVEL RESINS AND PHOTORESIST COMPOSITIONS COMPRISING SAME PUF60, CAD, RARA DPP8 4433/4885DPP9 4410/4885ALDH1A1 2478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.