Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28261002 | 0.81 | HPGD (0.49) | ACACBPLK1AKR1C3AKR1C2KMT2A | |
| SCHEMBL12999075 | 0.81 | ALDH1A1 (0.36) | KMT2ATAS1R3TAS1R1ALDH1A1ESR1 | |
| SCHEMBL11565132 | 0.80 | L3MBTL1 (0.43) | SLC6A4ALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL4011952 | 0.80 | LMNA (0.41) | GAASLC6A4ALDH1A1KDM4ELMNA | |
| SCHEMBL11358790 | 0.80 | PLK1 (0.43) | ACACBPLK1AKR1C3AKR1C2KMT2A | |
| SCHEMBL1564938 | 0.79 | CYP1A2 (0.50) | KMT2AALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL8881032 | 0.79 | ESR1 (0.54) | KMT2AALDH1A1MAPTALOX15LMNA | |
| SCHEMBL4013605 | 0.79 | L3MBTL1 (0.46) | KMT2AALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL4776154 | 0.79 | L3MBTL1 (0.45) | KMT2AALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL11564445 | 0.78 | SLC6A3 (0.46) | ACACBKMT2ASLC6A4ALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4207234-A | 4-Unsubstituted azetidinone derivatives and process for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-06-10 | — | — | US | disclosed |