Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 2/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011958 | 0.78 | MAPK1 (0.39) | KMT2AMEN1 | |
| SCHEMBL7846601 | 0.74 | ALDH1A1 (0.49) | KMT2AMEN1LMNAALDH1A1CYP1A2 | |
| SCHEMBL7833590 | 0.73 | ALDH1A1 (0.38) | DAOKMT2AMEN1ATMLMNA | |
| SCHEMBL7843105 | 0.71 | NPC1 (0.38) | DAOKMT2AMEN1 | |
| SCHEMBL5084496 | 0.70 | HPGD (0.43) | KMT2AMEN1LMNAALDH1A1CYP3A4 | |
| SCHEMBL7508732 | 0.70 | NPC1 (0.36) | DAOKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL7842196 | 0.70 | CES2 (0.46) | DAOKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL7843738 | 0.70 | ELANE (0.38) | DAOKMT2AMEN1LMNA | |
| SCHEMBL7834093 | 0.70 | CES2 (0.41) | DAOKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL7843947 | 0.70 | CES2 (0.41) | DAOALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4207234-A | 4-Unsubstituted azetidinone derivatives and process for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-06-10 | — | — | US | disclosed |