Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3538846 | 0.84 | ALOX5 (0.46) | ALOX5SMN1; SMN2HPGDPKMGSK3B | |
| SCHEMBL7642306 | 0.79 | ALOX5 (0.49) | ALOX5SMN1; SMN2PKMGSK3BKMT2A | |
| Hydrochloric Acid SCHEMBL5214794 | 0.79 | ALOX5 (0.46) | ALOX5SMN1; SMN2HPGDPKMGSK3B | |
| SCHEMBL10760527 | 0.72 | ALOX5 (0.36) | ALOX5SMN1; SMN2HPGDPKMGSK3B | |
| SCHEMBL2608970 | 0.71 | ALOX5 (0.47) | ALOX5PKMGSK3BATMRAB9A | |
| SCHEMBL2994556 | 0.70 | ALOX5 (0.44) | ALOX5SMN1; SMN2HPGDPKMGSK3B | |
| SCHEMBL7550562 | 0.70 | ALOX5 (0.41) | ALOX5KDM4ECYP1A2CYP2C19 | |
| SCHEMBL3541270 | 0.69 | ALOX5 (0.50) | ALOX5SMN1; SMN2PKMGSK3BKMT2A | |
| SCHEMBL9000694 | 0.69 | CES2 (0.56) | ALOX5HPGDKMT2AMEN1GAA | |
| SCHEMBL13792082 | 0.69 | ALOX5 (0.43) | ALOX5SMN1; SMN2HPGDPKMGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4208423-A | Anticholinergic bronchodilators | SYNTEX INC. (US) | 1980-06-17 | — | — | US | disclosed |
| EP-0012071-A1 | Azoniaspiro derivatives, process for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1980-06-11 | — | — | EP | disclosed |