Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11468486 | 0.84 | ALOX5 (0.45) | ALOX5SMN1; SMN2HPGDPKMGSK3B | |
| Hydrochloric Acid SCHEMBL5214794 | 0.81 | ALOX5 (0.46) | ALOX5SMN1; SMN2HPGDPKMGSK3B | |
| SCHEMBL13225708 | 0.80 | ABCB11 (0.38) | SMN1; SMN2HPGDPKMALDH1A1KMT2A | |
| SCHEMBL3541270 | 0.79 | ALOX5 (0.50) | ALOX5SMN1; SMN2PKMGSK3BKMT2A | |
| SCHEMBL6611730 | 0.75 | ALDH1A1 (0.55) | SMN1; SMN2HPGDPKMALDH1A1KMT2A | |
| SCHEMBL2994556 | 0.71 | ALOX5 (0.44) | ALOX5SMN1; SMN2HPGDPKMGSK3B | |
| SCHEMBL13792082 | 0.70 | ALOX5 (0.43) | ALOX5SMN1; SMN2HPGDPKMGSK3B | |
| SCHEMBL7642306 | 0.69 | ALOX5 (0.49) | ALOX5SMN1; SMN2PKMGSK3BKMT2A | |
| SCHEMBL2162247 | 0.69 | ALOX5 (0.53) | ALOX5SMN1; SMN2HPGDPKMGSK3B | |
| SCHEMBL3534703 | 0.69 | ALDH1A1 (0.41) | SMN1; SMN2HPGDALDH1A1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101120000-B | Pyrazolopyrimidines | BAYER CROPSCIENCE AG | 2011-05-18 | — | — | CN | disclosed |
| US-7781439-B2 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2010-08-24 | — | — | US | disclosed |
| US-7781439-B2 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2010-08-24 | — | — | US | disclosed |
| US-7781439-B2 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2010-08-24 | — | — | US | disclosed |
| US-7629294-B2 | Pyrazolopyrimidines | BAYER CROPSCIENCE LP (DE) | 2009-12-08 | — | — | US | disclosed |
| US-7629294-B2 | Pyrazolopyrimidines | BAYER CROPSCIENCE LP (DE) | 2009-12-08 | — | — | US | disclosed |
| US-7629294-B2 | Pyrazolopyrimidines | BAYER CROPSCIENCE LP (DE) | 2009-12-08 | — | — | US | disclosed |
| US-20080287463-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2008-11-20 | — | — | US | disclosed |
| US-20080287463-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2008-11-20 | — | — | US | disclosed |
| US-20080287463-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2008-11-20 | — | — | US | disclosed |
| CN-101120000-A | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2008-02-06 | — | — | CN | disclosed |
| CN-101023078-A | 5-heterocyclyl pyrimidines | BAYER CROPSCIENCE AG (DE) | 2007-08-22 | — | — | CN | disclosed |
| EP-1791834-A1 | 5-HETEROCYCLYL PYRIMIDINES | Bayer CropScience Aktiengesellschaft (DE) | 2007-06-06 | — | — | EP | disclosed |
| EP-1718652-A2 | PYRAZOLOPYRIMIDINES FOR COMBATTING UNWANTED MICROORGANISMS | Bayer CropScience Aktiengesellschaft (DE) | 2006-11-08 | — | — | EP | disclosed |
| WO-2006029867-A1 | 5-HETEROCYCLYL PYRIMIDINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-03-23 | — | — | WO | disclosed |
| WO-2005082907-A2 | PYRAZOLOPYRIMIDINES FOR CONTROLLING UNDESIRED MICROORGANISMS | BAYER CROPSCIENCE AG (DE) | 2005-09-09 | — | — | WO | disclosed |
| US-20050187224-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287463-A1 | Pyrazolopyrimidines | RRP15, RPLP2, DPYD | ALOX5 3062/4885SMN1; SMN2 3995/4885HPGD 1139/4885 |
| US-20050187224-A1 | Pyrazolopyrimidines | P2RX5, P2RX4, P2RX1 | ALOX5 2632/4885SMN1; SMN2 3995/4885HPGD 1756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.