Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11508178 | 0.90 | TRPM8 (0.36) | TRPM8KDM4EMEN1NPC1MITF | |
| SCHEMBL11472079 | 0.82 | TRPM8 (0.46) | TRPM8KDM4EMEN1NPC1MITF | |
| SCHEMBL11472081 | 0.82 | TRPM8 (0.46) | TRPM8KDM4EMEN1NPC1MITF | |
| SCHEMBL11551320 | 0.82 | ALDH1A1 (0.43) | KDM4EMEN1NPC1MITFALDH1A1 | |
| SCHEMBL11508179 | 0.81 | LMNA (0.33) | TRPM8KDM4EALDH1A1SMN1; SMN2CHRM2 | |
| SCHEMBL11478753 | 0.81 | TRPM8 (0.43) | TRPM8KDM4EMEN1NPC1MITF | |
| SCHEMBL11338200 | 0.81 | TRPM8 (0.43) | TRPM8KDM4EMEN1NPC1MITF | |
| SCHEMBL11478366 | 0.79 | TRPM8 (0.35) | TRPM8KDM4EMEN1NPC1MITF | |
| SCHEMBL11478376 | 0.79 | TRPM8 (0.35) | TRPM8KDM4EMEN1NPC1MITF | |
| SCHEMBL11468501 | 0.78 | CNR2 (0.37) | TRPM8KDM4EMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4199589-A | N-(2-Aminocycloheptyl)acylanilides and methods to treat depression | SZMUSZKOVICZ JACOB (US) | 1980-04-22 | — | — | US | disclosed |
| US-4172898-A | N-(2-aminocycloheptyl)acylanilides | THE UPJOHN COMPANY (US) | 1979-10-30 | — | — | US | disclosed |