Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.34 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | AGER | Q15109 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11508179 | 0.97 | LMNA (0.33) | CNR2MAPTLMNAALDH1A1HTT | |
| SCHEMBL11478756 | 0.82 | LMNA (0.39) | CNR2MAPTLMNAALDH1A1HTT | |
| SCHEMBL11551323 | 0.81 | CNR2 (0.38) | CNR2MAPTLMNAALDH1A1HTT | |
| SCHEMBL11472080 | 0.79 | LMNA (0.38) | CNR2MAPTLMNAALDH1A1NPY2R | |
| SCHEMBL11478373 | 0.79 | CNR1 (0.33) | CNR2MAPTLMNAALDH1A1POLB | |
| SCHEMBL11468500 | 0.78 | TRPM8 (0.40) | ALDH1A1TRPM8KDM4ESIGMAR1NPC1 | |
| SCHEMBL11456610 | 0.77 | ALDH1A1 (0.34) | CNR2MAPTLMNAALDH1A1HTT | |
| SCHEMBL11472843 | 0.75 | PGR (0.33) | LMNAALDH1A1POLB | |
| SCHEMBL11472016 | 0.75 | LMNA (0.37) | CNR2LMNAALDH1A1TRPM8KDM4E | |
| SCHEMBL11508178 | 0.74 | TRPM8 (0.36) | LMNAALDH1A1HTTPOLBTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4199589-A | N-(2-Aminocycloheptyl)acylanilides and methods to treat depression | SZMUSZKOVICZ JACOB (US) | 1980-04-22 | — | — | US | disclosed |
| US-4172898-A | N-(2-aminocycloheptyl)acylanilides | THE UPJOHN COMPANY (US) | 1979-10-30 | — | — | US | disclosed |