Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11468632 | 1.00 | PABPC1 (0.38) | PABPC1TSHRGRM5ALDH1A1CYP2D6 | |
| SCHEMBL11461117 | 0.84 | GRM5 (0.33) | PABPC1TSHRGRM5CTDSP1INMT | |
| SCHEMBL11461742 | 0.75 | ACHE (0.40) | PABPC1TSHRALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL11461741 | 0.75 | ACHE (0.40) | PABPC1TSHRALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL11340270 | 0.74 | LMNA (0.53) | PABPC1TSHRGRM5ALDH1A1CTDSP1 | |
| SCHEMBL11340269 | 0.74 | LMNA (0.53) | PABPC1TSHRGRM5ALDH1A1CTDSP1 | |
| Hydrochloric Acid SCHEMBL11466308 | 0.71 | INMT (0.41) | PABPC1TSHRGRM5INMT | |
| Hydrochloric Acid SCHEMBL11466307 | 0.71 | INMT (0.41) | PABPC1TSHRGRM5INMT | |
| SCHEMBL11541143 | 0.69 | CTDSP1 (0.48) | PABPC1TSHRGRM5ALDH1A1CTDSP1 | |
| SCHEMBL4815252 | 0.67 | SLC6A2 (0.40) | SLC6A3LMNAGAASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4181661-A | SCHIZOPHRENIA, PSYCHOLOGICAL DISORDERS | MERCK & CO., INC. (US) | 1980-01-01 | — | — | US | disclosed |