Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 10/20 | 0.59 |
| ▸ | COMT | P21964 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3968481 | 0.82 | KIF11 (0.57) | KIF11COMTMAP4K4CA12CA9 | |
| SCHEMBL28950239 | 0.79 | KIF11 (0.54) | KIF11COMTMAP4K4CA12CA9 | |
| SCHEMBL1740256 | 0.79 | KIF11 (0.54) | KIF11COMTMAP4K4CA12CA9 | |
| SCHEMBL1549633 | 0.79 | KIF11 (0.54) | KIF11CA12CA9SCN2A | |
| SCHEMBL29818212 | 0.79 | KIF11 (0.59) | KIF11MAP4K4ALOX5APFEN1 | |
| SCHEMBL11483670 | 0.77 | ALDH1A1 (0.56) | KIF11DYRK1ADYRK2SCN2A | |
| SCHEMBL2694870 | 0.77 | KMT2A (0.42) | KIF11COMTMEN1NPC1RAB9A | |
| SCHEMBL29914837 | 0.76 | KIF11 (0.78) | KIF11CA1CA2 | |
| SCHEMBL197238 | 0.76 | KIF11 (0.78) | KIF11CA1CA2 | |
| SCHEMBL13410633 | 0.76 | KIF11 (0.78) | KIF11CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4209621-A | TRANQUILIZERS | AMERICAN CYANAMID COMPANY (US) | 1980-06-24 | — | — | US | disclosed |